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Article

Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways.

Biological psychiatry - 1 Jul 2014

Gelernter Joel, Kranzler Henry R, Sherva Richard, Koesterer Ryan, Almasy Laura, Zhao Hongyu, Farrer Lindsay A

Abstract excerpt

BACKGROUND: We report a genome-wide association study (GWAS) of two populations, African-American and European-American (AA, EA) for opioid dependence (OD) in three sets of subjects, to identify pathways, genes, and alleles important in OD risk. METHODS: The design employed three phases (on the basis of separate sample collections). Phase 1 included our discovery GWAS dataset consisting of 5697 subjects (58% AA)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 24143882
DOI: 10.1016/j.biopsych.2013.08.034
PMCID: PMC3992201

Genes

KCNG2
KCNC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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