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Article

Genomewide linkage scan for opioid dependence and related traits.

American journal of human genetics - 1 May 2006

Gelernter Joel, Panhuysen Carolien, Wilcox Marsha, Hesselbrock Victor, Rounsaville Bruce, Poling James, Weiss Roger, Sonne Susan, Zhao Hongyu, Farrer Lindsay, Kranzler Henry R

Abstract excerpt

Risk of opioid dependence is genetically influenced. We recruited a sample of 393 small nuclear families (including 250 full-sib and 46 half-sib pairs), each with at least one individual with opioid dependence. Subjects underwent a detailed evaluation of substance dependence-related traits. As planned a priori to reduce heterogeneity, we used cluster analytic methods to identify opioid dependence-related symptom...

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Identifiers

PMID: 16642432
DOI: 10.1086/503631
PMCID: PMC1474044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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