A novel germline <i>JAK2</i> mutation in familial myeloproliferative neoplasms

Abstract excerpt

To the Editor Familial clustering of myeloproliferative neoplasms (MPN) has been reported but the molecular basis is still unknown 1, 2. Common mutations involved in the pathogenesis of MPN, such as JAK2, MPL, CBL, and TET2 mutations are mainly somatically acquired also in familial cases 1, 3, 4. Germline mutations underlying familial syndromes resembling MPN have been reported: germline mutations in...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Eosinophilic Disorders and Syndromes
• Share to Kruppel-like factors research
• Share to Myeloproliferative Neoplasms: Diagnosis and Treatment