Article
Vertical transmission of hepatitis C virus: a tale of multiple outcomes.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2013
Escobar-Gutiérrez Alejandro, Soudeyns Hugo, Larouche Ariane, Carpio-Pedroza Juan Carlos, Martinez-Guarneros Armando, Vazquez-Chacon Carlos A, Fonseca-Coronado Salvador, Yamasaki Lilian H T, Ruiz-Tovar Karina, Cruz-Rivera Mayra
Abstract excerpt
Globally, hepatitis C virus (HCV) infection affects approximately 130 million people and 3 million new infections occur annually. HCV is also recognized as an important cause of chronic liver disease in children. The absence of proofreading properties of the HCV RNA polymerase leads to a highly error prone replication process, allowing HCV to escape host immune response. The adaptive nature of HCV evolution...
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