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Article

Rapid hepatitis C virus divergence among chronically infected individuals.

Journal of clinical microbiology - 1 Feb 2013

Cruz-Rivera Mayra, Carpio-Pedroza Juan Carlos, Escobar-Gutiérrez Alejandro, Lozano Daniela, Vergara-Castaneda Arely, Rivera-Osorio Pilar, Martinez-Guarneros Armando, Chacon Carlos A Vazquez, Fonseca-Coronado Salvador, Vaughan Gilberto

Abstract excerpt

Here, we analyze the viral divergence among hepatitis C virus (HCV) chronic cases infected with genotype 1. The intrahost viral evolution was assessed by deep sequencing using the 454 Genome Sequencer platform. The results showed a rapid nucleotide sequence divergence. This notorious short-term viral evolution is of the utmost importance for the study of HCV transmission, because direct links between related...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23224093
DOI: 10.1128/JCM.03042-12
PMCID: PMC3553878

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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