Article
Genetic variations in IL6 and IL12B decreasing the risk for psoriasis.
Immunology letters - 1 Jan 2000
Boca Andreea Nicoleta, Talamonti Marina, Galluzzo Marco, Botti Elisabetta, Vesa Stefan Cristian, Chimenti Sergio, Buzoianu Anca Dana, Costanzo Antonio
Abstract excerpt
BACKGROUND: Psoriasis is a chronic inflammatory skin disorder. Recent studies associated a number of genetic variants to this immune-mediated pathology. OBJECTIVE: This study aims to assess whether the association between the non-susceptibility allelic variants of IL12B single-nucleotide polymorphism (SNPs) rs3212227 and rs6887695, IL23R SNPs rs11209026 and rs7530511, IL6 SNP rs1800795 and HLA-Cw6 could be...