Article
Resequencing of the IL12B gene in psoriasis patients with the rs6887695/rs3212227 risk genotypes.
Cytokine - 1 Oct 2012
Eiris Noemí, Santos-Juanes Jorge, Coto-Segura Pablo, Gómez Juan, Alvarez Victoria, Morales Blanca, Queiro Rubén, Díaz Marta, Corao Ana I, López-Corte Katia, Coto Eliecer
Abstract excerpt
BACKGROUND AND AIMS: Recent genomic surveys have identified IL12B as susceptibility locus for psoriasis (Ps). Our aim was to replicate the association between IL12B SNPs and Ps. In addition, we sequenced the IL12B gene in several patients to identify new variants that could explain the disease-risk. RESULTS: A total of 304 Ps-patients and 422 healthy controls (all Caucasian Spanish) were genotyped for three IL12B...
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