Article
The multiple forms of bovine seminal ribonuclease: structure and stability of a C-terminal swapped dimer.
FEBS letters - 29 Nov 2013
Sica Filomena, Pica Andrea, Merlino Antonello, Russo Krauss Irene, Ercole Carmine, Picone Delia
Abstract excerpt
Bovine seminal ribonuclease (BS-RNase) acquires an interesting anti-tumor activity associated with the swapping on the N-terminal. The first direct experimental evidence on the formation of a C-terminal swapped dimer (C-dimer) obtained from the monomeric derivative of BS-RNase, although under non-native conditions, is here reported. The X-ray model of this dimer reveals a quaternary structure different from that...
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