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Article

Chain termini cross-talk in the swapping process of bovine pancreatic ribonuclease.

Biochimie - 1 May 2012

Merlino Antonello, Picone Delia, Ercole Carmine, Balsamo Anna, Sica Filomena

Abstract excerpt

3D domain swapping is the process by which two or more protein molecules exchange part of their structure to form intertwined dimers or higher oligomers. Bovine pancreatic ribonuclease (RNase A) is able to swap the N-terminal α-helix (residues 1-13) and/or the C-terminal β-strand (residues 116-124), thus forming a variety of oligomers, including two different dimers. Cis-trans isomerization of the Asn113-Pro114...

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Identifiers

PMID: 22273774
DOI: 10.1016/j.biochi.2012.01.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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