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Article

The frequency of KRAS and BRAF mutations in intrahepatic cholangiocarcinomas and their correlation with clinical outcome.

Human pathology - 1 Dec 2013

Robertson Scott, Hyder Omar, Dodson Rebecca, Nayar Suresh K, Poling Justin, Beierl Katie, Eshleman James R, Lin Ming-Tseh, Pawlik Timothy M, Anders Robert A

Abstract excerpt

The incidence of intrahepatic cholangiocarcinoma is increasing worldwide. The prognosis of intrahepatic cholangiocarcinoma is poor, and a better understanding of intrahepatic cholangiocarcinoma tumor biology is needed to more accurately predict clinical outcome and to suggest potential targets for more effective therapies. v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) and BRAF are frequently mutated...

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Source

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Identifiers

PMID: 24139215
DOI: 10.1016/j.humpath.2013.07.026
PMCID: PMC3838441

Genes

BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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