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Article

Molecular profiling of cholangiocarcinoma shows potential for targeted therapy treatment decisions.

Human pathology - 1 Jul 2013

Voss Jesse S, Holtegaard Leonard M, Kerr Sarah E, Fritcher Emily G Barr, Roberts Lewis R, Gores Gregory J, Zhang Jun, Highsmith W Edward, Halling Kevin C, Kipp Benjamin R

Abstract excerpt

Cholangiocarcinoma is a highly lethal cancer of the biliary tract. The intrahepatic subtype of cholangiocarcinoma is increasing in incidence globally. Despite technologic advancements over the past decade, little is known about the somatic changes that occur in these tumors. The goal of this study was to determine the frequency of common oncogenes in resected cholangiocarcinoma specimens that could provide...

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Topics

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Share to Bile Duct Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Neoplastic

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Source

Identifiers

PMID: 23391413
DOI: 10.1016/j.humpath.2012.11.006

Genes

BRAF
EGFR
IDH1
KRAS
MET
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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