Article
Genetic Determinants of Outcome in Intrahepatic Cholangiocarcinoma.
Hepatology (Baltimore, Md.) - 1 Sept 2021
Boerner Thomas, Drill Esther, Pak Linda M, Nguyen Bastien, Sigel Carlie S, Doussot Alexandre, Shin Paul, Goldman Debra A, Gonen Mithat, Allen Peter J, Balachandran Vinod P, Cercek Andrea, Harding James, Solit David B, Schultz Nikolaus, Kundra Ritika, Walch Henry, D'Angelica Michael I, DeMatteo Ronald P, Drebin Jeffrey, Kemeny Nancy E, Kingham T Peter, Simpson Amber L, Hechtman Jaclyn F, Vakiani Efsevia, Lowery Maeve A, Ijzermans J N M, Buettner S, Koerkamp B Groot, Doukas M, Chandwani Rohit, Jarnagin William R
Abstract excerpt
BACKGROUND AND AIM: Genetic alterations in intrahepatic cholangiocarcinoma (iCCA) are increasingly well characterized, but their impact on outcome and prognosis remains unknown. APPROACH AND RESULTS: This bi-institutional study of patients with confirmed iCCA (n = 412) used targeted next-generation sequencing of primary tumors to define associations among genetic alterations, clinicopathological variables, and...
Topics
Join the communities discussing this publication.