Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High throughput molecular profiling reveals differential mutation patterns in intrahepatic cholangiocarcinomas arising in chronic advanced liver diseases.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 May 2014

Jang Sejin, Chun Sung-Min, Hong Seoung-Mo, Sung Chang Ohk, Park Hosub, Kang Hyo Jeong, Kim Kyu-pyo, Lee Young Joo, Yu Eunsil

Abstract excerpt

Intrahepatic cholangiocarcinomas occur mostly in the normal liver but they also arise in chronic advanced liver diseases. However, genetic differences between two groups have yet to be examined. High throughput mass spectrometry-based platform was used to interrogate mutations in intrahepatic cholangiocarcinomas and to compare the mutation profiles between 43 intrahepatic cholangiocarcinomas with normal liver and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bile Duct Neoplasms
Share to Bile Ducts, Intrahepatic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholangiocarcinoma

Share to Chromogranins

Share to GTP-Binding Protein alpha Subunits, Gs

Share to GTP Phosphohydrolases

Share to Liver Diseases

Share to MutL Protein Homolog 1

Source

Identifiers

PMID: 24186137
DOI: 10.1038/modpathol.2013.194

Genes

GNAS
KRAS
EGFR
MLH1
PTEN
APC
BRAF
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High throughput molecular profiling reveals differential mutation patterns in intrahepatic cholangiocarcinomas arising in chronic advanced liver diseases.PMID 24186137Read ↗

Molecular profiling of cholangiocarcinoma shows potential for targeted therapy treatment decisions.Semantic proximity Read ↗

Molecular Profile of Intrahepatic CholangiocarcinomaSemantic proximity Read ↗

Comprehensive Molecular Profiling of Intrahepatic and Extrahepatic Cholangiocarcinomas: Potential Targets for InterventionSemantic proximity Read ↗

Cholangiocarcinoma Heterogeneity Revealed by Multigene Mutational Profiling: Clinical and Prognostic Relevance in Surgically Resected Patients.Semantic proximity Read ↗

Molecular profiling of intrahepatic and extrahepatic cholangiocarcinoma using next generation sequencing.Semantic proximity Read ↗

Differential isocitrate dehydrogenase 1 and isocitrate dehydrogenase 2 mutation-related landscape in intrahepatic cholangiocarcinoma.Semantic proximity Read ↗

Molecular Pathogenesis of Cholangiocarcinoma: Implications for Disease Classification and Therapy.Semantic proximity Read ↗

Recent Advances in Pathology of Intrahepatic CholangiocarcinomaSemantic proximity Read ↗

Mutational landscape of intrahepatic cholangiocarcinoma.Semantic proximity Read ↗

Comprehensive Analysis of Genomic Mutation Signature and Tumor Mutation Burden for Prognosis of Intrahepatic CholangiocarcinomaSemantic proximity Read ↗

Intrahepatic cholangiocarcinoma: current management and emerging therapies.Semantic proximity Read ↗

Update on cholangiocarcinoma: potential impact of genomic studies on clinical management.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.