Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic alterations of <i>KRAS</i> and <i>TP53</i> in intrahepatic cholangiocarcinoma associated with poor prognosis

1 Jan 2023

Abstract excerpt

Abstract The aim of this study is to investigate certain genetic features of intrahepatic cholangiocarcinoma (ICCA). A total of 12 eligible ICCA patients were enrolled, and tumor tissues from the patients were subjected to next-generation sequencing of a multi-genes panel. Tumor mutation burden (TMB), mutated genes, copy number variants (CNVs), and pathway enrichment analysis were performed. The median TMB was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholangiocarcinoma and Gallbladder Cancer Studies
Share to Pancreatic and Hepatic Oncology Research
Share to Pediatric Hepatobiliary Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37483430
DOI: 10.1515/biol-2022-0652

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic alterations of <i>KRAS</i> and <i>TP53</i> in intrahepatic cholangiocarcinoma associated with poor prognosisPMID 37483430Read ↗

Mutational landscape of intrahepatic cholangiocarcinoma.Semantic proximity Read ↗

Two classes of intrahepatic cholangiocarcinoma defined by relative abundance of mutations and copy number alterations.Semantic proximity Read ↗

Comprehensive Analysis of Genomic Mutation Signature and Tumor Mutation Burden for Prognosis of Intrahepatic CholangiocarcinomaSemantic proximity Read ↗

A relationship between genetic sequencing and prognosis for combined hepatocellular carcinoma and cholangiocarcinomaSemantic proximity Read ↗

Molecular Profile of Intrahepatic CholangiocarcinomaSemantic proximity Read ↗

Comprehensive analysis of genomic mutation signature and tumor mutation burden for prognosis of intrahepatic cholangiocarcinoma.Semantic proximity Read ↗

Genetic Determinants of Outcome in Intrahepatic Cholangiocarcinoma.Semantic proximity Read ↗

TP53 /KRAS Co-Mutations Create Divergent Prognosis Signatures in Intrahepatic CholangiocarcinomaSemantic proximity Read ↗

Comprehensive molecular profiling of intrahepatic cholangiocarcinoma in the Chinese population and therapeutic experience.Semantic proximity Read ↗

Comprehensive molecular profiling of intrahepatic cholangiocarcinoma in the Chinese population and therapeutic experienceSemantic proximity Read ↗

Differential isocitrate dehydrogenase 1 and isocitrate dehydrogenase 2 mutation-related landscape in intrahepatic cholangiocarcinoma.Semantic proximity Read ↗

Intrahepatic Cholangiocarcinoma: Genomic Heterogeneity Between Eastern and Western PatientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.