Article
A Preliminary Study on Racial Differences in HMOX1, NFE2L2, and TGFβ1 Gene Polymorphisms and Radiation-Induced Late Normal Tissue Toxicity.
International journal of radiation oncology, biology, physics - 1 Oct 2015
Alam Asim, Mukhopadhyay Nitai D, Ning Yi, Reshko Leonid B, Cardnell Robert J G, Alam Omair, Rabender Christopher S, Yakovlev Vasily A, Walker Linda, Anscher Mitchell S, Mikkelsen Ross B
Abstract excerpt
PURPOSE: This study tested whether racial differences in genetic polymorphisms of 4 genes involved in wound repair and response to radiation can be used to predict the occurrence of normal tissue late effects of radiation therapy and indicate potential therapeutic targets. METHODS AND MATERIALS: This prospective study examined genetic polymorphisms that modulate the expression of 4 genes involved in inflammation...
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