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Article

DNA methylation levels of CYP2R1 and CYP24A1 predict vitamin D response variation.

The Journal of steroid biochemistry and molecular biology - 1 Oct 2014

Zhou Yu, Zhao Lan-Juan, Xu Xiaojing, Ye An, Travers-Gustafson Dianne, Zhou Boting, Wang Hong-Wei, Zhang Weidong, Lee Hamm L, Deng Hong-Wen, Recker Robert R, Lappe Joan M

Abstract excerpt

Factors contributing to the variability of serum 25-hydroxyvitamin D [25(OH)D] in response to a given dose of vitamin D supplementation are largely unknown. We examined whether DNA methylation levels of Cytochrome P450 (CYP) enzymes (CYP2R1, CYP24A1, CYP27A1, and CYP27B1) are potential biomarkers predicting vitamin D response variation. We randomized 446 white postmenopausal women to a calcium and vitamin D...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24128439
DOI: 10.1016/j.jsbmb.2013.10.004
PMCID: PMC3984616

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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