Article
Correlation of CYP2R1 gene promoter methylation with circulating vitamin D levels among healthy adults.
The Indian journal of medical research - 1 Aug 2023
Varadharajan Ashvin, Sibin M K, Athira S V, Ghosh Arijit Kumar, Misra Pratibha
Abstract excerpt
Background & objectives: Despite being a tropical country, vitamin D deficiency is highly prevalent in India with studies indicating 40-99 per cent prevalence. Apart from calcium and phosphate metabolism, vitamin D is involved in cell cycle regulation, cardiovascular, hepatoprotection. The metabolism of vitamin D is regulated by vitamin D tool genes (CYP2R1/CYP27B1/CYP24A1/VDR). The promoter regions of some of...
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