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Article

Environmental, personal, and genetic determinants of response to vitamin D supplementation in older adults.

The Journal of clinical endocrinology and metabolism - 1 Jul 2014

Waterhouse Mary, Tran Bich, Armstrong Bruce K, Baxter Catherine, Ebeling Peter R, English Dallas R, Gebski Val, Hill Christine, Kimlin Michael G, Lucas Robyn M, Venn Alison, Webb Penelope M, Whiteman David C, Neale Rachel E

Abstract excerpt

CONTEXT AND OBJECTIVE: Suboptimal vitamin D status can be corrected by vitamin D supplementation, but individual responses to supplementation vary. We aimed to examine genetic and nongenetic determinants of change in serum 25-hydroxyvitamin D (25(OH)D) after supplementation. DESIGN AND PARTICIPANTS: We used data from a pilot randomized controlled trial in which 644 adults aged 60 to 84 years were randomly...

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Identifiers

PMID: 24694335
DOI: 10.1210/jc.2013-4101

Genes

HERC2
MCM6
TYRP1
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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