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Article

Vitamin D, DNA methylation, and breast cancer.

Breast cancer research : BCR - 11 Jul 2018

O'Brien Katie M, Sandler Dale P, Xu Zongli, Kinyamu H Karimi, Taylor Jack A, Weinberg Clarice R

Abstract excerpt

BACKGROUND: Vitamin D has anticarcinogenic and immune-related properties and may protect against some diseases, including breast cancer. Vitamin D affects gene transcription and may influence DNA methylation. METHODS: We studied the relationships between serum vitamin D, DNA methylation, and breast cancer using a case-cohort sample (1070 cases, 1277 in subcohort) of non-Hispanic white women. For our primary...

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Topics

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Share to 25-Hydroxyvitamin D3 1-alpha-Hydroxylase
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Gene Expression Regulation, Neoplastic

Share to Receptors, Calcitriol

Share to Vitamin D

Share to Vitamin D3 24-Hydroxylase

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 29996894
DOI: 10.1186/s13058-018-0994-y
PMCID: PMC6042268

Genes

RXRA
DHCR7
NADSYN1
EPHX1
SMARCD2
SPN
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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