Association study of 83 candidate genes for bipolar disorder in chromosome 6q selected using an evidence-based prioritization algorithm.

doi:10.1002/ajmg.b.32200

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Article

Association study of 83 candidate genes for bipolar disorder in chromosome 6q selected using an evidence-based prioritization algorithm.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Dec 2013

Bigdeli T Bernard, Maher Brion S, Zhao Zhongming, Sun Jingchun, Medeiros Helena, Akula Nirmala, McMahon Francis J, Carvalho Celia, Ferreira Susana R, Azevedo Maria H, Knowles James A, Pato Michele T, Pato Carlos N, Fanous Ayman H

Abstract excerpt

BACKGROUND: Prior genome-scans of bipolar disorder have revealed chromosome 6q22 as a promising candidate region. However, linkage disequilibrium (LD) mapping studies have yet to identify replicated susceptibility loci. METHODS: We analyzed 1,422 LD-tagging single nucleotide polymorphisms (SNPs) in 83 genes to test single-marker and locus-wide evidence of association with bipolar disorder in the NIMH Genetics...

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PMID: 24123842
DOI: 10.1002/ajmg.b.32200
PMCID: PMC12888025

Genes

CCNC
NT5DC1

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Source receipt: pubmed, retrieved 7 Sept 2026.

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