Linkage disequilibrium mapping of the chromosome 6q21-22.31 bipolar I disorder susceptibility locus.

doi:10.1002/ajmg.b.30942

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Article

Linkage disequilibrium mapping of the chromosome 6q21-22.31 bipolar I disorder susceptibility locus.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2010

Fan Jinbo, Ionita-Laza Iuliana, McQueen Matthew B, Devlin Bernie, Purcell Shaun, Faraone Stephen V, Allen Michael H, Bowden Charles L, Calabrese Joseph R, Fossey Mark D, Friedman Edward S, Gyulai Laszlo, Hauser Peter, Ketter Terence B, Marangell Lauren B, Miklowitz David J, Nierenberg Andrew A, Patel Jayendra K, Sachs Gary S, Thase Michael E, Molay Francine B, Escamilla Michael A, Nimgaonkar Vishwajit L, Sklar Pamela, Laird Nan M, Smoller Jordan W

Abstract excerpt

We previously reported genome-wide significant evidence for linkage between chromosome 6q and bipolar I disorder (BPI) by performing a meta-analysis of original genotype data from 11 genome scan linkage studies. We now present follow-up linkage disequilibrium mapping of the linked region utilizing 3,047 single nucleotide polymorphism (SNP) markers in a case-control sample (N = 530 cases, 534 controls) and...

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PMID: 19308960
DOI: 10.1002/ajmg.b.30942
PMCID: PMC4067321

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