Article
Initial genome scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 1, 6, 8, 10, and 12.
American journal of medical genetics - 31 May 1997
Rice J P, Goate A, Williams J T, Bierut L, Dorr D, Wu W, Shears S, Gopalakrishnan G, Edenberg H J, Foroud T, Nurnberger J, Gershon E S, Detera-Wadleigh S D, Goldin L R, Guroff J J, McMahon F J, Simpson S, MacKinnon D, McInnis M, Stine O C, DePaulo J R, Blehar M C, Reich T
Abstract excerpt
A report on an initial genome screen on 540 individuals in 97 families was collected as part of the NIMH Genetics Initiative on Bipolar Disorder. Families were ascertained to be informative for genetic linkage and underwent a common ascertainment and assessment protocol at four clinical sites. The sample was genotyped for 65 highly polymorphic markers from chromosomes 1, 6, 8, 10, and 12. The average intermarker...
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