Article
Nanotopographical effects on mesenchymal stem cell morphology and phenotype.
Journal of cellular biochemistry - 1 Feb 2014
Tsimbouri Penelope, Gadegaard Nikolaj, Burgess Karl, White Kate, Reynolds Paul, Herzyk Pawel, Oreffo Richard, Dalby Matthew J
Abstract excerpt
There is a rapidly growing body of literature on the effects of topography and critically, nanotopography on cell adhesion, apoptosis and differentiation. Understanding the effects of nanotopography on cell adhesion and morphology and the consequences of cell shape changes in the nucleus, and consequently, gene expression offers new approaches to the elucidation and potential control of stem cell differentiation....
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