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Nanotopographic Regulation of Human Mesenchymal Stem Cell Osteogenesis

8 Nov 2017

Abstract excerpt

Mesenchymal stem cell (MSC) differentiation can be manipulated by nanotopographic interface providing a unique strategy to engineering stem cell therapy and circumventing complex cellular reprogramming. However, our understanding of the nanotopographic-mechanosensitive properties of MSCs and the underlying biophysical linkage of the nanotopography-engineered stem cell to directed commitment remains elusive. Here,...

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PMID: 29116745
DOI: 10.1021/acsami.7b16314

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