Article
A genomics approach in determining nanotopographical effects on MSC phenotype.
Biomaterials - 1 Mar 2013
Tsimbouri Penelope M, Murawski Kate, Hamilton Graham, Herzyk Pawel, Oreffo Richard O C, Gadegaard Nikolaj, Dalby Matthew J
Abstract excerpt
Topography and its effects on cell adhesion, morphology, growth and differentiation are well documented. Thus, current advances with the use of nanotopographies offer promising results in the field of regenerative medicine. Studies have also shown nanotopographies to have strong effects on stem cell self-renewal and differentiation. What is less clear however is what mechanotransductive mechanisms are employed by...
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