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Article

EGFR, KRAS, BRAF, and PIK3CA characterization in squamous cell anal cancer.

Histology and histopathology - 1 Apr 2014

Martin Vittoria, Zanellato Elena, Franzetti-Pellanda Alessandra, Molinari Francesca, Movilia Alessandra, Paganotti Alessia, Deantonio Letizia, De Dosso Sara, Assi Agnese, Crippa Stefano, Boldorini Renzo, Mazzucchelli Luca, Saletti Piercarlo, Frattini Milo

Abstract excerpt

BACKGROUND: Combined chemoradiation therapy is the gold standard in the treatment of squamous cell anal cancer (SCAC). However, even if the response rate is very high, many patients eventually relapse or experience a reccurrence, thus requiring an invasive surgical procedure that has severe side effects. Most SCAC tumors overexpress epidermal growth factor receptor (EGFR); therefore, it is reasonable to consider...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to In Situ Hybridization, Fluorescence

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Source

Identifiers

PMID: 24122611
DOI: 10.14670/HH-29.10.513

Genes

EGFR
BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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