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Article

Epidermal growth factor receptor (EGFR)-RAS signaling pathway in penile squamous cell carcinoma.

PloS one - 1 Jan 2013

Gou Hong-Feng, Li Xiang, Qiu Meng, Cheng Ke, Li Long-Hao, Dong Hang, Chen Ye, Tang Yuan, Gao Feng, Zhao Feng, Men Hai-Tao, Ge Jun, Su Jing-Mei, Xu Feng, Bi Feng, Gao Jian-Jun, Liu Ji-Yan

Abstract excerpt

Penile Squamous Cell Carcinoma (SCC) is a rare cancer with poor prognosis and limited response to conventional chemotherapy. The genetic and epigenetic alterations of Epidermal Growth Factor Receptor (EGFR)-RAS-RAF signaling in penile SCC are unclear. This study aims to investigate four key membe...

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Share to Carcinoma, Squamous Cell
Share to Lymphatic Metastasis
Share to Neoplasm Grading

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

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Source

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Identifiers

PMID: 23637996
DOI: 10.1371/journal.pone.0062175
PMCID: PMC3634795

Genes

EGFR
BRAF
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23637996-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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