Article
K-ras status in squamous cell anal carcinoma (SCC): it's time for target-oriented treatment?
Cancer chemotherapy and pharmacology - 1 Dec 2009
Zampino Maria Giulia, Magni Elena, Sonzogni Angelica, Renne Giuseppe
Abstract excerpt
PURPOSE: Squamous cell anal carcinoma (SCC) is an uncommon disease comprising only 1-5% of all intestinal tumours. SCC is now considered the prototype for the successful application of conservative treatment as chemoradiation instead of aggressive surgery. The EGFR status and k-ras mutations in SCC of the anal canal has not been well investigated. The purpose of our evaluation was to give information about this...
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