Article
Low-density lipoprotein levels and not mutation status predict intima-media thickness in familial hypercholesterolemia.
Annals of vascular surgery - 1 Feb 2014
Fahed Akl C, Habib Robert H, Nemer Georges M, Azar Sami T, Andary Rabih R, Arabi Mariam T, Moubarak Elie M, Bitar Fadi F, Haddad Fady F
Abstract excerpt
BACKGROUND: Intima-media thickness (IMT) is a well-described marker of cardiovascular disease. In this study we aim to determine whether low-density lipoprotein (LDL) levels and disease-related mutation status can predict IMT in patients with severe familial hypercholesterolemia (FH) referred for or on LDL apheresis. METHODS: Genetic screening, lipid profile testing, and IMT measurements were performed on a...
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