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Article

Genetic mutations, regression of Achilles tendon thickness, and cardiovascular events among patients with familial hypercholesterolemia.

Atherosclerosis - 1 Jan 2022

Tada Hayato, Okada Hirofumi, Nohara Atsushi, Takamura Masayuki, Kawashiri Masa-Aki

Abstract excerpt

BACKGROUND AND AIMS: Achilles tendon thickness (ATT) can be regressed through LDL-lowering in patients with familial hypercholesterolemia (FH). We aimed to determine factors associated with regression of ATT and its role in development of major adverse cardiovascular events (MACE). METHODS: Patients with clinically diagnosed FH (N = 1,050, male/female = 490/560) were retrospectively assessed. FH-related gene...

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PMID: 34871818
DOI: 10.1016/j.atherosclerosis.2021.11.031

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