Article
Increased intima-media thickness in carriers of the ldl-receptor defective gene versus noncarriers with newly detected asymptomatic severe hypercholesterolemia.
Echocardiography (Mount Kisco, N.Y.) - 1 Feb 2011
Vladimirova-Kitova Lyudmila G, Deneva-Koicheva Tania I
Abstract excerpt
BACKGROUND: The data on the examination of early vascular alterations in carriers of molecular defects of the low-density lipoprotein-receptor (LDL-R) in comparison to noncarriers with severe hypercholesterolemia are controversial. AIMS: To examine the difference between patients with severe hypercholesterolemia, who are carriers and noncarriers of LDL-R defective gene, with respect to their functional...
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