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Article

Assessment of carotid atherosclerosis in normocholesterolemic individuals with proven mutations in the low-density lipoprotein receptor or apolipoprotein B genes.

Circulation. Cardiovascular genetics - 1 Aug 2011

Huijgen Roeland, Vissers Maud N, Kindt Iris, Trip Mieke D, de Groot Eric, Kastelein John J P, Hutten Barbara A

Abstract excerpt

BACKGROUND: Genetic cascade screening for heterozygous familial hypercholesterolemia (FH) revealed that 15% of individuals given this diagnosis do not exhibit elevated low-density lipoprotein cholesterol (LDL-C) levels. We assessed whether cardiovascular risk for these individuals differs from that of hypercholesterolemic FH heterozygotes and unaffected relatives. METHODS AND RESULTS: Individuals aged 18 to 55...

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Share to Apolipoproteins B
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cholesterol, LDL

Share to Hyperlipoproteinemia Type II

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Source

Identifiers

PMID: 21642693
DOI: 10.1161/CIRCGENETICS.110.959239

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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