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Article

Genetic and metabolic factors predicting risk of cardiovascular disease in familial hypercholesterolemia.

The Netherlands journal of medicine - 1 Oct 2001

Smilde T J, van Wissen S, Wollersheim H, Kastelein J J, Stalenhoef A F

Abstract excerpt

Familial hypercholesterolemia is a hereditary metabolic disorder characterised by high low-density lipoprotein cholesterol levels and an extreme risk of premature cardiovascular disease. In patients with heterozygous familial hypercholesterolemia a substantial variation is seen in both the severity of the hypercholesterolemia and onset of atherosclerotic disease symptoms. We discuss the contribution of additional...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11578794
DOI: 10.1016/s0300-2977(01)00155-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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