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Article

Squalene epoxidase as a target for manipulation of squalene levels in the yeast Saccharomyces cerevisiae.

FEMS yeast research - 1 Mar 2014

Garaiová Martina, Zambojová Veronika, Simová Zuzana, Griač Peter, Hapala Ivan

Abstract excerpt

Squalene is a valuable natural substance with several biotechnological applications. In the yeast Saccharomyces cerevisiae, it is produced in the isoprenoid pathway as the first precursor dedicated to ergosterol biosynthesis. The aim of this study was to explore the potential of squalene epoxidase encoded by the ERG1 gene as the target for manipulating squalene levels in yeast. Highest squalene levels (over...

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PMID: 24119181
DOI: 10.1111/1567-1364.12107

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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