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Article

Transcriptional regulation of the squalene synthase gene (ERG9) in the yeast Saccharomyces cerevisiae.

Biochimica et biophysica acta - 14 Apr 1999

Kennedy M A, Barbuch R, Bard M

Abstract excerpt

The ergosterol biosynthetic pathway is a specific branch of the mevalonate pathway. Since the cells requirement for sterols is greater than for isoprenoids, sterol biosynthesis must be regulated independently of isoprenoid biosynthesis. In this study we explored the transcriptional regulation of squalene synthase (ERG9) in Saccharomyces cerevisiae, the first enzyme dedicated to the synthesis of sterols. A mutant...

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Source

Identifiers

PMID: 10209263
DOI: 10.1016/s0167-4781(99)00035-4

Genes

HAP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Transcriptional regulation of the squalene synthase gene (ERG9) in the yeast Saccharomyces cerevisiae.PMID 10209263Read ↗

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