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Article

Accumulation of squalene in a microalga Chlamydomonas reinhardtii by genetic modification of squalene synthase and squalene epoxidase genes.

PloS one - 1 Jan 2015

Kajikawa Masataka, Kinohira Seiko, Ando Akira, Shimoyama Miki, Kato Misako, Fukuzawa Hideya

Abstract excerpt

Several microalgae accumulate high levels of squalene, and as such provide a potentially valuable source of this useful compound. However, the molecular mechanism of squalene biosynthesis in microalgae is still largely unknown. We obtained the sequences of two enzymes involved in squalene synthesis and metabolism, squalene synthase (CrSQS) and squalene epoxidase (CrSQE), from the model green alga Chlamydomonas...

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Identifiers

PMID: 25764133
DOI: 10.1371/journal.pone.0120446
PMCID: PMC4357444

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Source receipt: pubmed, retrieved 7 Sept 2026.

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