Article
Plasma clusterin levels and the rs11136000 genotype in individuals with mild cognitive impairment and Alzheimer's disease.
Current Alzheimer research - 1 Nov 2013
Mullan Gemma M, McEneny Jane, Fuchs Marc, McMaster Cyril, Todd Stephen, McGuinness Bernadette, Henry Mark, Passmore A Peter, Young Ian S, Johnston Janet A
Abstract excerpt
AIM: Substantial evidence links atherosclerosis and Alzheimer's disease (AD). Apolipoproteins, such as apolipoprotein E, have a causal relationship with both diseases. The rs11136000 SNP within the CLU gene, which encodes clusterin (apolipoprotein J), is also associated with increased AD risk. The aim of this study was to investigate the relationship between plasma clusterin and the rs11136000 genotype in mild...
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