Article
Plasma clusterin and the risk of Alzheimer disease.
JAMA - 6 Apr 2011
Schrijvers Elisabeth M C, Koudstaal Peter J, Hofman Albert, Breteler Monique M B
Abstract excerpt
CONTEXT: Variants in the clusterin gene are associated with the risk of Alzheimer disease (AD) and clusterin levels have been found to be increased in brain and cerebrospinal fluid of patients with AD. Plasma clusterin was reported to be associated with brain atrophy, baseline disease severity, and rapid clinical progression in patients with AD. OBJECTIVE: To evaluate the potential of plasma clusterin as a...
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