Article
Association of the Alzheimer's disease clusterin risk allele with plasma clusterin concentration.
Journal of Alzheimer's disease : JAD - 1 Jan 2011
Schürmann Britta, Wiese Birgitt, Bickel Horst, Weyerer Siegfried, Riedel-Heller Steffi G, Pentzek Michael, Bachmann Cadja, Williams Julie, van den Bussche Hendrik, Maier Wolfgang, Jessen Frank
Abstract excerpt
A variant within the clusterin gene has been recently associated with increased risk for Alzheimer's disease (AD) in genome wide association studies. Here we tested the association of the respective single nucleotide polymorphisms (rs11136000) with plasma concentration of clusterin in 67 AD subjects and 191 cognitively unimpaired elderly individuals. We observed an association of the rs11136000 AD-risk variant...
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