Increased risk of developing digestive tract cancer in subjects carrying the PLCE1 rs2274223 A>G polymorphism: evidence from a meta-analysis.

doi:10.1371/journal.pone.0076425

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Increased risk of developing digestive tract cancer in subjects carrying the PLCE1 rs2274223 A>G polymorphism: evidence from a meta-analysis.

PloS one - 1 Jan 2013

Zhang Xunlei, Zhang Yangmei, Gu Dongying, Cao Chunxiang, Zhang Qi, Xu Zhi, Gong Yongling, Chen Jinfei, Tang Cuiju

Abstract excerpt

BACKGROUND: To date, the association between phospholipase C epsilon 1 (PLCE1) rs2274223 A>G and risk of digestive tract cancer (DTC) remains inconclusive. To derive a more precise estimation of the association, we conducted a meta-analysis on all eligible case-control studies involving 8281 cases and 10,532 controls. METHODS: A comprehensive search was conducted to identify all eligible studies of PLCE1...

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PMID: 24116107
DOI: 10.1371/journal.pone.0076425
PMCID: PMC3792074

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PLCE1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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