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Article

CTLA-4 polymorphisms and predisposition to digestive system malignancies: a meta-analysis of 31 published studies.

World journal of surgical oncology - 16 Mar 2020

Li Jien, Wang Wenping, Sun Yanyan, Zhu Yeduo

Abstract excerpt

BACKGROUND: The results of genetic association studies regarding cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) polymorphisms and digestive system malignancies were controversial. The authors designed this meta-analysis to more precisely estimate relationships between CTLA-4 polymorphisms and digestive system malignancies by pooling the results of related studies. METHODS: The authors searched PubMed,...

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CTLA-4 Antigen
Digestive System Neoplasms
Genetic Predisposition to Disease
Polymorphism, Genetic
Publication Bias

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Identifiers

PMID: 32178688
DOI: 10.1186/s12957-020-1806-2
PMCID: PMC7077159

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