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Article

PLCE1 polymorphism and upper gastrointestinal cancer risk: a meta-analysis.

PloS one - 1 Jan 2013

Hao Ning-Bo, He Ya-Fei, Zhang Dan, Luo Gang, Chen Bai-Jun, Zhang Yao, Yang Shi-Ming

Abstract excerpt

BACKGROUND: In recent years, the PLCE1 rs2274223 polymorphism has been extensively investigated as a potential risk factor for upper gastrointestinal cancers, including squamous cell carcinoma (ESCC) and gastric cancer. However, the results of these studies have been inconsistent. METHODS: A meta-analysis of 13 case-control studies was performed including more than 11,000 subjects with genotyped PLCE1 rs2274223...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Squamous Cell

Share to Gastrointestinal Neoplasms

Share to PLCE1 gene

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Share to Phosphoinositide Phospholipase C

Share to Polymorphism, Single Nucleotide

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Source

Open in PubMed Open full text

Identifiers

PMID: 23826241
DOI: 10.1371/journal.pone.0067229
PMCID: PMC3691110

Genes

PLCE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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