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Genetic Characteristics of the Human Hepatic Stellate Cell Line LX-2

8 Oct 2013

Abstract excerpt

The human hepatic cell line LX-2 has been described as tool to study mechanisms of hepatic fibrogenesis and the testing of antifibrotic compounds. It was originally generated by immortalisation with the Simian Vacuolating Virus 40 (SV40) transforming (T) antigen and subsequent propagation in low serum conditions. Although this immortalized line is used in an increasing number of studies, detailed genetic...

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PMID: 24116068
DOI: 10.1371/journal.pone.0075692

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