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Article

A Comprehensive Karyotypic Study on Human Hepatocellular Carcinoma by Spectral Karyotyping

1 Nov 2000

Abstract excerpt

The current paucity of cytogenetic information on hepatocellular carcinoma (HCC) reflects the difficulties in culturing hepatocytes in vitro. Here, we report on the successful culture of 15 HCC cases. Chromosome aneuploidy ranging from a near-diploid to hyperhexaploid karyotype was found, but their complete karyotypic interpretations were hampered by the presence of many unidentifiable rearrangements. Spectral...

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PMID: 11050057
DOI: 10.1053/jhep.2000.19349

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