Article
HuH-7 reference genome profile: complex karyotype composed of massive loss of heterozygosity.
Human cell - 1 Jul 2018
Kasai Fumio, Hirayama Noriko, Ozawa Midori, Satoh Motonobu, Kohara Arihiro
Abstract excerpt
Human cell lines represent a valuable resource as in vitro experimental models. A hepatoma cell line, HuH-7 (JCRB0403), has been used extensively in various research fields and a number of studies using this line have been published continuously since it was established in 1982. However, an accurate genome profile, which can be served as a reliable reference, has not been available. In this study, we performed...
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