Article
Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis
10 Dec 2004
Abstract excerpt
BACKGROUND: Hepatic stellate cells (HSCs) are a major fibrogenic cell type that contributes to collagen accumulation during chronic liver disease. With increasing interest in developing antifibrotic therapies, there is a need for cell lines that preserve the in vivo phenotype of human HSCs to elucidate pathways of human hepatic fibrosis. We established and characterised two human HSC cell lines termed LX-1 and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.