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Article

Frequent aneuploidy among normal human hepatocytes.

Gastroenterology - 1 Jan 2012

Duncan Andrew W, Hanlon Newell Amy E, Smith Leslie, Wilson Elizabeth M, Olson Susan B, Thayer Matthew J, Strom Stephen C, Grompe Markus

Abstract excerpt

Murine hepatocytes become polyploid and then undergo ploidy reversal and become aneuploid in a dynamic process called the ploidy conveyor. Although polyploidization occurs in some types of human cells, the degree of aneuploidy in human hepatocytes is not known. We isolated hepatocytes derived from healthy human liver samples and determined chromosome number and identity using traditional karyotyping and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22057114
DOI: 10.1053/j.gastro.2011.10.029
PMCID: PMC3244538

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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