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"The Good, the Bad, and the Ugly" - About Diverse Phenotypes of Hepatic Stellate Cells in the Liver.

Cellular and molecular gastroenterology and hepatology - 1 Jan 2024

Bogomolova Alexandra, Balakrishnan Asha, Ott Michael, Sharma Amar Deep

Abstract excerpt

Hepatic stellate cells (HSCs) and their activated derivatives, often referred to as myofibroblasts (MFs), play a key role in progression of chronic liver injuries leading to fibrosis, cirrhosis, and hepatocellular carcinoma. Until recently, MFs were considered a homogenous cell type majorly due to lack of techniques that allow complex molecular studies at a single-cell resolution. Recent technical advancements in...

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Identifiers

PMID: 38216053
DOI: 10.1016/j.jcmgh.2024.01.002
PMCID: PMC10900761

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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