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Article

SUMOylation regulates the SNF1 protein kinase.

Proceedings of the National Academy of Sciences of the United States of America - 22 Oct 2013

Simpson-Lavy Kobi J, Johnston Mark

Abstract excerpt

The AMP-activated protein kinase (AMPK) is a major stress sensor of mammalian cells. AMPK's homolog in the yeast Saccharomyces cerevisiae, the SNF1 protein kinase, is a central regulator of carbon metabolism that inhibits the Snf3/Rgt2-Rgt1 glucose sensing pathway and activates genes involved in respiration. We present evidence that glucose induces modification of the Snf1 catalytic subunt of SNF1 with the small...

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Identifiers

PMID: 24108357
DOI: 10.1073/pnas.1304839110
PMCID: PMC3808588

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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