Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Roles of the glycogen-binding domain and Snf4 in glucose inhibition of SNF1 protein kinase.

The Journal of biological chemistry - 11 Jul 2008

Momcilovic Milica, Iram Surtaj H, Liu Yang, Carlson Marian

Abstract excerpt

The SNF1/AMP-activated protein kinase (AMPK) family is required for adaptation to metabolic stress and energy homeostasis. The gamma subunit of AMPK binds AMP and ATP, and mutations that affect binding cause human disease. We have here addressed the role of the Snf4 (gamma) subunit in regulating SNF1 protein kinase in response to glucose availability in Saccharomyces cerevisiae. Previous studies of mutant cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AMP-Activated Protein Kinases
Share to Catalytic Domain

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Energy Metabolism

Share to Glucose

Share to Glycogen

Share to Glycogen Synthase

Share to Multienzyme Complexes

Share to Protein Structure, Secondary

Source

Open in PubMed Open full text

Identifiers

PMID: 18474591
DOI: 10.1074/jbc.M803624200
PMCID: PMC2443652

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Roles of the glycogen-binding domain and Snf4 in glucose inhibition of SNF1 protein kinase.PMID 18474591Read ↗

Mutations in the gal83 glycogen-binding domain activate the snf1/gal83 kinase pathway by a glycogen-independent mechanism.Semantic proximity Read ↗

ADP regulates SNF1, the Saccharomyces cerevisiae homolog of AMP-activated protein kinase.Semantic proximity Read ↗

Snf1/AMPK promotes S-phase entrance by controlling CLB5 transcription in budding yeast.Semantic proximity Read ↗

Biochemical and functional studies on the regulation of the Saccharomyces cerevisiae AMPK homolog SNF1.Semantic proximity Read ↗

Roles of two protein phosphatases, Reg1-Glc7 and Sit4, and glycogen synthesis in regulation of SNF1 protein kinase.Semantic proximity Read ↗

Heterotrimer-independent regulation of activation-loop phosphorylation of Snf1 protein kinase involves two protein phosphatases.Semantic proximity Read ↗

Activation and inhibition of Snf1 kinase activity by phosphorylation within the activation loop.Semantic proximity Read ↗

Function of mammalian LKB1 and Ca2+/calmodulin-dependent protein kinase kinase alpha as Snf1-activating kinases in yeast.Semantic proximity Read ↗

Domain fusion between SNF1-related kinase subunits during plant evolution.Semantic proximity Read ↗

Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases.Semantic proximity Read ↗

Feedback Control of Snf1 Protein and Its Phosphorylation Is Necessary for Adaptation to Environmental Stress.Semantic proximity Read ↗

Protein kinase A contributes to the negative control of Snf1 protein kinase in Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.